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MOTS-c Peptide: Mitochondrial-Derived Research Reference

May 11, 2026

MOTS-c Peptide: Mitochondrial-Derived Research Reference

MOTS-c is one of the first characterised mitochondrial-derived peptides — a 16-residue reference in cellular energy-metabolism research.

MOTS-c is a 16-residue peptide encoded within the mitochondrial 12S rRNA region. Published in-vitro literature reports AMPK-pathway activation, GLUT4 translocation and glucose-metabolism endpoints in skeletal muscle cell cultures.

  • 16 residues, mitochondrially-encoded.
  • AMPK-pathway activation reported in published research.
  • Frequently studied alongside SS-31 and NAD+ precursors in longevity research.
  • Batch identifier and synthesis date traceable to the lot record
  • HPLC purity ≥98% (typically ≥99% for peptides under 30 residues)
  • LC-MS confirmed monoisotopic or average mass within ±0.5 Da of theoretical
  • Counterion identity and content (acetate or trifluoroacetate) reported
  • Bacterial endotoxin and residual solvents per the analytical method
Research use only. All information on this page is provided strictly for in-vitro and laboratory research reference. Nothing in this article is medical, therapeutic, dosing, or performance advice for human or veterinary use.

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