Cagrilintide (amylin) vs semaglutide (GLP-1) — two independent satiety mechanisms that are frequently studied together.
This is the rare comparison where both compounds are best understood as complementary rather than competitive. Their receptor systems do not overlap.
| Attribute | Cagrilintide | Semaglutide |
|---|---|---|
| Class | Amylin analog | GLP-1 agonist |
| Receptors | AMY1/2/3 (amylin/CT family) | GLP-1R |
| Half-life | ~7 days | ~7 days |
| Primary endpoint driver | Satiety, gastric emptying | Glucose-dependent insulin, satiety |
Research use only. All information on this page is provided strictly for in-vitro and laboratory research reference. Nothing in this article is medical, therapeutic, dosing, or performance advice for human or veterinary use.
